这本书提供了一个全面和最先进的概述血友病管理通过审查所有最新的进展和前沿信息在这个快速发展的领域。由于血友病患者经常受到关节问题的影响，它也为肌肉骨骼表现的外科治疗提供了明确的指导。
第一部分专门讨论该疾病的病理生理学（区分血友病A和B）、遗传学、药物治疗（包括替代和非替代治疗）、基因治疗以及与血友病携带者相关的生活质量问题。第二部分则侧重于关节问题，从关节健康评估和疼痛控制到急性关节炎和血友病性关节病的外科治疗，即放射关节切除术、全关节置换术和关节镜下关节清创术。
这本书由来自治疗血友病和相关关节问题的主要机构的专家撰写，为血液学家、整形外科医生、康复医师、放射科医生和药学研究人员提供了宝贵的资源。
Advances in Hemophilia Treatment: From Genetics to Joint Health
This book offers a comprehensive and state of the art overview of hemophilia management by reviewing all most recent advances and cutting edge information in this fast evolving field. As hemophilia patients are often affected by joint problems it also provides clear guidance on the surgical treatment of musculo-skeletal manifestations.
The first part is devoted to the disease’s pathophysiology (differentiating hemophilia A and B), genetics, pharmacotherapy – including replacement and non-replacement therapy – and gene therapy, as well as quality of life issues – also related to hemophilia carriers. The second part is then focused on joint problems, ranging from joint health assessment and pain control to surgical treatment of acute hemarthrosis and hemophilic arthropathy, i.e. radiosynovectomy, total joint arthroplasty and arthroscopic joint debridement.
Written by experts drawn from leading institutions involved in treatment of hemophilia and related joint problems, this book offers a valuable resource to hematologists, orthopedic surgeons, rehabilitation physicians, radiologists, and pharmacy researchers.
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