在基因密码首次被破译时，信使RNA中信息解码的动态性质是出乎意料的。我们现在知道，单个密码子的意义和读出过程的框架都可以通过特定信使RNA中的信息来修改。这本书描述了这种“重新编码”现象，揭示了mRNAs中另一层信息的多样性，这些信息丰富了基因的表达。重新编码的知识对于理解病毒和从细菌到太古代到植物再到人类的所有生物体中基因的组织和表达至关重要，使重新编码与所有生物科学相关。
Recoding: Expansion of Decoding Rules Enriches Gene Expression
The dynamic nature of decoding the information in messenger RNA was unanticipated at the time the genetic code was first deciphered. We now know that both the meaning of individual codons and the framing of the readout process can be modified by information in specific messenger RNAs. This book describes this “Recoding” phenomenon, revealing the diversity of an additional layer of information in mRNAs that serves to enrich the expression of genes. Knowledge of recoding is essential for understanding the organization and expression of genes in viruses and all organisms ranging from bacteria to archeae to plants to humans, making Recoding pertinent to all biological sciences.
OR
