这本参考书全面回顾了DNA技术在法医学中的重要性。在介绍了用于法医DNA分型的理论、基本原理、工具和技术之后，总结了用于解决刑事和民事案件的各种技术，包括常染色体STR、Y-STR、X-STR、线粒体DNA和NGS，如父权纠纷、残肢鉴定以及性侵犯和谋杀案件中的罪犯鉴定。它还概述了各种疾病的基于DNA的基因诊断，并讨论了DNA分型在药物反应中的作用，以及动物和植物的非人类DNA图谱在法医学调查中的应用。最后，本书探讨了内部质量控制在保持DNA图谱高质量方面的作用。
Handbook of DNA Profiling
This reference book comprehensively reviews the significance of DNA technology in forensic science. After presenting the theory, basic principles, tools and techniques that are used in forensic DNA typing, it summarizes various techniques, including autosomal STR, Y-STR, X-STR, mitochondrial DNA and NGS, used in solving both criminal as and civil cases, such as paternity disputes, identification of mutilated remains, and culprit identification in sexual assault and murder cases. It also provides an overview of DNA-based genetic diagnostics for various diseases, and discusses the role of DNA typing in drug reactions, as well as the application of non-human DNA profiling of animals and plants in forensic science investigations. Lastly, the book examines the role of internal quality control in maintaining the high quality of DNA profiling.
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