第三版是关于制备主要类型糖苷的最广为人知的方法的综合和扩展研究,涵盖了用于制备简单且具有挑战性的糖苷的经典和最新的糖基化反应,这些糖苷目前用作有效的抗病毒和抗肿瘤药物,或用于细胞生物学中酶检测的荧光底物。此外,新版还提供了更多的糖苷方法学示例,用于制备复杂的糖缀合物,如糖蛋白、鞘糖脂和神经节苷脂,用作佐剂或合成候选疫苗。
Synthesis and Characterization of Glycosides
This third edition is a comprehensive and extended study about the best known approaches for preparing the main types of glycosides, covering the classic and more recent glycosylation reactions used for preparing simple and challenging glycosides currently used as potent antiviral and antineoplastic drugs, or fluorogenic substrates used for enzymatic detection in cell biology. Besides, this new edition provides more examples of the glycosidic methodologies followed for preparing complex glycoconjugates such as glycoproteins and glycosphingolipids and gangliosides used as adjuvants or as synthetic vaccines candidates.
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