本书结合医学和工程知识,在促进以患者为中心的先天性心脏病(CHD)治疗方法的背景下,展示工程建模应用(主要是计算的,但也是实验的)。
在介绍了工程工具的基本概念之后,它讨论了建模和工程技术(例如计算流体力学、流体结构相互作用、结构模拟、虚拟手术、高级图像分析、3D打印)在特定先天性心脏病中的应用。它还提供了一些临床案例研究,描述了在实际临床实践中的应用。最后一节重点介绍外科培训、咨询和患者沟通的重要性。
考虑到CHD修复前后独特的解剖结构安排,以及不同的手术策略和设备选择(例如支架),在这一医学领域,患者特定的方法当然是必要的,工程学正在帮助我们提高对个体患者及其特定解剖和生理学的理解。
为了加强工程师和临床医生之间必要对话的想法,这本书不仅由两位心脏病专家和两位生物工程师编辑,而且每一章都由一位临床医生和一位工程师撰写,在描述不同CHD的最先进模型时,将这两种声音结合起来。
Modelling Congenital Heart Disease: Engineering a Patient-specific Therapy
This book combines medicinal and engineering knowledge to present engineering modelling applications (mainly computational, but also experimental) in the context of facilitating a patient-centred approach to treating congenital heart disease (CHD).
After introducing the basic concepts of engineering tools, it discusses modelling and the applications of engineering techniques (e.g. computational fluid dynamics, fluid-structure interaction, structural simulations, virtual surgery, advanced image analysis, 3D printing) in specific congenital heart diseases. It also offers a number of clinical case studies describing the applications in real-life clinical practice. The final section focuses on the importance of surgical training, counselling and patient communication.
Considering the unique anatomical arrangement pre/post repair in CHD, as well as the different surgical strategy and device options (e.g. stents) for interventions, a patient-specific approach is certainly warranted in this area of medicine, and engineering is helping improve our understanding of individual patients and their particular anatomy and physiology.
To reinforce the idea of a necessary dialogue between engineers and clinicians, this book has not only been edited by two cardiologists and two bioengineers, but each chapter has been written by a clinician and an engineer, incorporating both voices in the description of state-of-the-art models for different CHDs.
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