运动生理学中的氧化应激揭示了模型系统和健康及疾病中的人类在细胞、组织和全身水平上对不同氧化还原调节运动模式的关键生理反应和适应。虽然机制细节尚不清楚，但关键的细胞内氧化还原指数似乎随着年龄的增长而失调。因此，老年人对急性耐力运动的有益分子反应会下降。最近的研究表明，通过补充线粒体靶向辅酶Q10六周来操纵线粒体氧化还原稳态，可以显著改善老年人的身体功能；i、 e.通过控制氧化还原环境，可以最大限度地发挥运动的益处。这本书中描述的研究表明，在心血管疾病、神经退行性变和癌症方面存在显著的翻译潜力。一个国际研究团队记录了氧化还原生物学在健康和疾病中的重要性，尤其是当运动是治疗许多疾病和疾病的临床有用工具时。
特征
相关标题
德雷珀·N·H·马歇尔。运动生理学促进健康和运动表现（ISBN 978-0-2737-7872-1）
《分子运动生理学：导论》（ISBN 978-0-4156-0788-9）
Oxidative Eustress in Exercise Physiology
Oxidative Eustress in Exercise Physiology unravels key physiological responses and adaptations to different redox-regulated exercise paradigms at the cell, tissue, and whole-body level in model systems and humans in health and disease. While the mechanistic details are still unclear, key intracellular redox indices seem to be dysregulated with age. Consequently, beneficial molecular responses to acute endurance exercise decline in older individuals. Recent research suggests that manipulating mitochondrial redox homeostasis by supplementing with the mitochondria-targeted coenzyme Q10 for six weeks markedly improves physical function in older adults; i.e. it may be possible to maximise the benefits of exercise by manipulating the redox environment. The research described in this book suggests that significant translational potential exists with respect to cardiovascular disease, neurodegeneration and cancer. An international team of researchers documents the importance of redox biology in health and disease, especially when exercise is a clinically useful tool for the treatment of many diseases and conditions.
Features
Related Titles
Draper, N. & H. Marshall. Exercise Physiology for Health and Sports Performance (ISBN 978-0-2737-7872-1)
Wackerhage, H., ed. Molecular Exercise Physiology: An Introduction (ISBN 978-0-4156-0788-9)
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