这本三卷集的第二本书《肿瘤生物学中的离子转运》帮助读者获得癌症病理生理学的全面知识。作者强调，离子转运蛋白、通道和转运蛋白（统称为转运组）与癌症的发展和进展密切相关。近90%的恶性肿瘤疾病起源于上皮细胞，其功能在很大程度上取决于转运组。本卷通过显示离子转运蛋白的失调表达和/或功能与绝大多数肿瘤疾病的恶性程度相关，重点介绍分子原理。
From Malignant Transformation to Metastasis: Ion Transport in Tumor Biology
This second book of the three-volume collection “Ion Transport in Tumor Biology” helps readers gain comprehensive knowledge of the pathophysiology of cancer. The authors highlight that ion transport proteins, channels and transporters – collectively referred to as the transportome – are significantly involved in the development and progression of cancer. Nearly 90% of malignant tumor diseases originate from epithelial cells, the function of which, for the most part, is based on the transportome. This volume focuses on molecular principles by showing that dysregulated expression and/or function of ion transporters have been correlated with malignancy in the vast majority of tumor diseases.
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